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Genetics and Developmental Biology
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In which order should the following steps be done to identify a quantitative trait locus (QTL) gene ...
lindsaykinz
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In which order should the following steps be done to identify a quantitative trait locus (QTL) gene ...
In which order should the following steps be done to identify a quantitative trait locus (QTL) gene that contributes to the phenotypic variation in a trait?
I.
DNA and protein sequence analyses are used to determine if there is a correlation with
phenotypic variation
II.
Each of the offspring is individually backcrossed with the same parent, usually the one
expressing the phenotype more strongly
III.
Lod scores are calculated for each genetic marker to find QTLs
IV.
The genotype of the progeny at genetic markers located every 5-10 cM is determined for each
introgression line
V.
Two individuals which exhibit the extremes of a specific phenotype are crossed
VI.
DNA sequence variants among introgression lines are analyzed to find candidate genes
▸ V, II, IV, III, VI, I
▸ I, V, III, II, IV, VI
▸ V, IV, II, III, I, VI
▸ I, II, IV, III, VI, V
▸ V, IV, III, II, VI, I
Textbook
Genetic Analysis: An Integrated Approach
Edition:
3
rd
Authors:
Sanders, Bowman
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V, II, IV, III, VI, I
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