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CarbonRobot CarbonRobot
wrote...
Posts: 393
Rep: 8 0
2 years ago
It is my understanding that when DNA mutates whether from stress, chemicals, or ionizing radiation the result is usually negative or neutral. If DNA mutations are unavoidable is there any evidence that anything would promote a mutation to be beneficial instead? Neutral is of course fine, but making things work better and move farther from the chance of cancer or senescence is important
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wrote...
Educator
2 years ago
If DNA mutations are unavoidable is there any evidence that anything would promote a mutation to be beneficial instead?

Mutations accumulate over an organisms lifetime usually without the organism "knowing". They may even be passed on to future generations if the mutation happened to occur in germline cells responsible for generating gametes. This is what lends to different alleles of the same genes -- variations in skin color/eye color is an example. What dictates an alleles usefulness is if it promotes reproduction and survival based on the environment in which the organism inhabits. Because the environment is really slow to change, we rarely see the benefits of any mutation in human beings.
CarbonRobot Author
wrote...
2 years ago
If DNA mutations are unavoidable is there any evidence that anything would promote a mutation to be beneficial instead?
Mutations accumulate over an organisms lifetime usually without the organism "knowing". They may even be passed on to future generations if the mutation happened to occur in germline cells responsible for generating gametes. This is what lends to different alleles of the same genes -- variations in skin color/eye color is an example. What dictates an alleles usefulness is if it promotes reproduction and survival based on the environment in which the organism inhabits. Because the environment is really slow to change, we rarely see the benefits of any mutation in human beings.

But certainly the negative mutations are easy to flag, and hence anything that isn't that must be ok?
wrote...
Educator
2 years ago
You could say that. Many spontaneous abortions (miscarriages) are said to be due to errors in the DNA either from conception or in the gametes themselves. I don't know how they confirm these, but it is certainly something to consider when making such a statement.
Source  https://biology-forums.com/index.php?action=gallery;sa=view;id=44314
CarbonRobot Author
wrote...
2 years ago
That is an interesting point.
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