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CarbonRobot CarbonRobot
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Posts: 393
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A year ago
Of people that get trigeminal neuralgia, which granted are very few, are there lifestyle or behavioral commonalities of everyone that gets it versus those that don't?
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wrote...
Staff Member
A year ago
Trigeminal neuralgia is characterized by overwhelming sensations of stabbing pain that may be momentary or may last for minutes or hours. When it is short-lived, the condition is also known as tic douloureux. Trigeminal neuralgia may be relieved by analgesics such as aspirin, ibuprofen, and acetaminophen. In severe cases, surgery may be performed to reduce pressure on the nerve or to sever it.

In postherpetic neuralgia, pain occurs at a site earlier affected by herpes zoster, or shingles, in which blisters develop on the skin along the path of a nerve. Postherpetic neuralgia may last for weeks or months after the illness, but the pain may be alleviated with analgesics.
- Master of Science in Biology
- Bachelor of Science
CarbonRobot Author
wrote...
A year ago
Trigeminal neuralgia is characterized by overwhelming sensations of stabbing pain that may be momentary or may last for minutes or hours. When it is short-lived, the condition is also known as tic douloureux. Trigeminal neuralgia may be relieved by analgesics such as aspirin, ibuprofen, and acetaminophen. In severe cases, surgery may be performed to reduce pressure on the nerve or to sever it.

In postherpetic neuralgia, pain occurs at a site earlier affected by herpes zoster, or shingles, in which blisters develop on the skin along the path of a nerve. Postherpetic neuralgia may last for weeks or months after the illness, but the pain may be alleviated with analgesics.

Yes but any genetic component or anything people do that leads to the disease? Anything one can avoid to reverse it? I am interested in the prediction factors.
wrote...
Staff Member
A year ago
There are several studies that have successfully linked trigeminal neuralgia (TN) to genetics. One such example is the one attached below.

From  what I've read, TN usually occurs spontaneously, but is sometimes associated with facial trauma or dental procedures. In fact, lots of people have the compressed nerve and never develop any symptoms. There is also the possibility that the TN is being compressed by an artery or vein due to which it is malfunctioning. But, for the most part, the exact pathophysiology of how vascular compression leads to TN remains speculative.

People with multiple sclerosis usually develop TN. Multiple sclerosis is a condition in which the myelin sheath surrounding the nerve degenerates, leaving the nerve unprotected, but I don't want you to freak out over this as I'm just stating every single possibility.
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- Master of Science in Biology
- Bachelor of Science
CarbonRobot Author
wrote...
A year ago Edited: A year ago, CarbonRobot
There are several studies that have successfully linked trigeminal neuralgia (TN) to genetics. One such example is the one attached below. From what I've read, TN usually occurs spontaneously, but is sometimes associated with facial trauma or dental procedures. In fact, lots of people have the compressed nerve and never develop any symptoms. There is also the possibility that the TN is being compressed by an artery or vein due to which it is malfunctioning. But, for the most part, the exact pathophysiology of how vascular compression leads to TN remains speculative. People with multiple sclerosis usually develop TN. Multiple sclerosis is a condition in which the myelin sheath surrounding the nerve degenerates, leaving the nerve unprotected, but I don't want you to freak out over this as I'm just stating every single possibility.

Thanks for the info. I wonder what genetic markers there are since it is fairly rare. Like 1/100th of a percent in the U.S.
Post Merge: A year ago

Also what exactly causes a blood vessel to put pressure on the nerve? Can't the blood vessel be removed or simply moved aside? My understanding is they use a tephlon pillow to put space between the nerve and blood vessel in one surgical procedure, but why do that? Are they so sure if they don't put a artificial barrier in there that it will reoccur or something? It doesn't sound like the initial cause is well known.
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