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Anonymous sara5656
wrote...
A month ago
Acromegaly is caused by hypersecretion of human growth hormone (hGH). Acromegaly is typically diagnosed in adults between the ages of 20–40.

Which of the following is a physiological consequence that is NOT a result of hypersecretion of hGH in adulthood?

a.
Elongation of the long bones

b.
Widening of the long bones

c.
Enlargement of the heart, liver, and spleen

d.
Thickening of the jaw





Acromegaly and gigantism are both caused by hypersecretion of

a.
ADH

b.
PTH

c.
hGH

d.
thyroxine







Growth hormone therapy has been widely used to help people with dwarfism and has helped certain individuals to become taller. Some recent studies have identified another hormone as beneficial when given in conjunction with growth hormone.

Which hormone would supplement or enhance the effects of hGH?

a.
calcitonin

b.
parathyroid

c.
inhibin

d.
cortisol







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Anonymousbio_man
wrote...
A month ago
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1st:

By the secretion of hGH enlargement of heart, liver and spleen occurs (visceral organs enlarge), long bones like femur, humerus enlarges, thickening of jaw occurs, but option 'b' Widening of the long bones is nonsense.

2nd:

hGH

3rd:

​​​​​​I believe it's cortisol. In Hormone therapy for dwarfism, Cortisol is used along with hGH because Cortisol increases the Growth hormone receptor mRNA levels. This effect occurs in a dose (Cortisol) dependent manner. Increased GH receptor mRNA expression leads to increase in GH receptors which enhances the affect of hGH.

Why not option b - Growth hormone stimulates parathyroid gland to secrete parathyroid hormone, which results in increased levels of parathyroid hormone. As such parathyroid hormone do not have any effect on Growth hormone .
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wrote...
A month ago
Thanks!
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