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oemBiology oemBiology
wrote...
Posts: 1245
A year ago Edited: A year ago, oemBiology
"The International Standard Atmosphere defines what consitutes a "normal" atmosphere. The sea level pressure is defined as 1.01325 bar (29.92 inches of mercury); the sea level temperature is defined as 15° C (59° F); and the temperature decreases at a lapse rate of 6.5° C / km (3.57° F / 1,000 feet). "

Based on this standard, for climbing a  mountain, is there any study to show on how much atmospheric pressure drop would starting to effect us?

How high should climber play attention on climbing a mountain?

Does anyone have any suggestions?
Thanks in advance

Post Merge: A year ago

https://ewscripps.brightspotcdn.com/dims4/default/5fc0548/2147483647/strip/true/crop/1920x1080+0+0/resize/2560x1440!/quality/90/?url=http%3A%2F%2Fewscripps-brightspot.s3.amazonaws.com%2Fd8%2F6d%2F6e4bee3e49448ff3c6e40042ff95%2Foxygen-levels.jpg
Post Merge: A year ago


Post Merge: A year ago

Based on sea level, 100% of oxygen, how much % of oxygen drop would alert us?
Does anyone have any suggestions?
Thanks in advance

Post Merge: A year ago

Pressure drops 50 mb, would this level have any effect on us?
Post Merge: A year ago

"Beyond 2,100 m the oxygen saturation of hemoglobin to form oxyhemoglobin begins to drastically decrease."

https://www.technology.org/2019/03/30/is-it-true-that-air-is-21-oxygen-for-most-of-us-not-really/

Would following different level of oxygen level effect Blood oxygen level?
oxygen constitutes 21 %.
oxygen constitutes 20 %.
oxygen constitutes 19 %.
oxygen constitutes 18 %.

Does anyone have any suggestions?
Thanks in advance

Post Merge: A year ago

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Replies
wrote...
Valued Member
Educator
A year ago
Hi oemBiology

The effects of limited oxygen can start to be felt by climbers at altitudes above 2400 meters above sea level. Above 3000 meters, climbers may experience acute mountain sickness, which can include symptoms such as severe headache, vomiting, and difficulty breathing. At even higher altitudes, such as those encountered on Mount Everest, climbers may experience more serious conditions such as high altitude pulmonary edema and high altitude cerebral edema, which can be life-threatening if not treated promptly.
oemBiology Author
wrote...
A year ago
Based on sea level, 100% of oxygen (1026mb), Pressure drops 50 mb, oxygen level would drop 5%.
Would the oxygen saturation of hemoglobin to form oxyhemoglobin begins to drastically decrease?
Do you have any suggestions?
Thank you very much for any suggestions (^v^)
wrote...
Valued Member
Educator
A year ago
Are you looking for something like this?

Source:

https://www.researchgate.net/publication/323843811_Predictors_of_Failure_in_Infant_Mandibular_Distraction_Osteogenesis
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oemBiology Author
wrote...
A year ago Edited: A year ago, oemBiology
For PaO2,
young adults around 90-100 mmHg
older adults around 75-85 mmHg



For older adults' PaO2 at 80 mmHg, SaO2 is 95.84, when Pressure drops 50 mb, oxygen level would drop 5%,
Would SaO2 drop 5% from 95.84 to 91 as well?
Does calculation work this way?

Do you have any suggestions?
Thank you very much for any suggestions (^v^)
wrote...
Valued Member
Educator
A year ago
You're asking is the drop proportional. From the curve provided in my previous post, the relationship is not linear. So my guess is no.
oemBiology Author
wrote...
A year ago
For PaO2 at 100 mmHg, SaO2 is 97.49%
when Pressure drops 50 mb, oxygen level would drop 5%,
PaO2 would also drop 5% from 100 to 95 mmHg, so
SaO2 level should be 97.25%, correct?
Do you have any suggestions?
Thank you very much for any suggestions (^v^)
wrote...
Valued Member
Educator
A year ago
For PaO2 at 100 mmHg, SaO2 is 97.49% when Pressure drops 50 mb, oxygen level would drop 5%, PaO2 would also drop 5% from 100 to 95 mmHg, so SaO2 level should be 97.25%, correct?

Yes, correct
oemBiology Author
wrote...
A year ago Edited: A year ago, oemBiology
When Pressure drops 50 mb, oxygen level would drop 5%,
It seems not making any sence for SaO2 dropping from  97.49% to 97.25%
Because PaO2 for older adults around 75-85 mmHg as starting points instead of 100 mmHg
Do you have any suggestions on how to correct this math?
Thank you very much for any suggestions (^v^)
wrote...
Valued Member
Educator
A year ago
Not sure why isn't not making sense? Here's a better graph showing the relationship between PaO2 and SaO2 versus altitude.



Source https://www.researchgate.net/figure/Relationship-of-altitude-and-barometric-pressure-to-PaO-2-PIO-2-and-SaO-2-Increasing_fig1_8542052

oemBiology Author
wrote...
A year ago
Younger adults' PaO2 around 90-100 mmHg.
Older adults' PaO2 around 75-85 mmHg.

When Pressure drops 50 mb, oxygen level would drop 5%,
Older adults would suffer more than younger adults, because of lower PaO2 75-85 mmHg.
Young adults' SaO2 level would drop from  97.49% to 97.25%
but how to determine older adults' SaO2 level? as oxygen level drop 5%
older adults SaO2 level should be lower than 97.25%, because of lower PaO2 level. (75-85 mmHg.)

Do you have any suggestions?
Thank you very much for any suggestions (^v^)

wrote...
Valued Member
Educator
A year ago
Hi oemBiology

This could be possibly what you're looking for (?)
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