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The nurse is reviewing the mechanism of goiter development in a client with nontoxic multinodular ...

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The nurse is reviewing the mechanism of goiter development in a client with nontoxic multinodular ...

The nurse is reviewing the mechanism of goiter development in a client with nontoxic multinodular goiters. Which statement best describes this process?

▸ Overall thyroid enlargement occurs without associated hypo- or hyperthyroidism, and is not induced by cysts, inflammation, or neoplasia.

▸ Thyroid enlargement occurs due to several growth factors, in addition to thyroid stimulating hormone (TSH), that cause some thyroid follicles to proliferate more than others.

▸ TSH receptor antibodies (TRAb) stimulate the TSH receptor to cause thyroid growth, goiter formation, and excessive secretion of thyroid hormones.

▸ Iodine deficiency causes some thyroid follicles to grow more quickly than to others, resulting in nodular changes and sequelae.

Textbook

Pathophysiology: Concepts of Human Disease

Edition: 1^st

Authors: Sorenson, Quinn, Klein

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