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Why does the nuclear membrane disappear during mitosis?

fishtaco

wrote...

11 years ago

Why does the nuclear membrane disappear during mitosis?

Science question that I'm stuck on. Why does the nuclear membrane of a cell disappear during the prophase of mitosis?

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smithstevee

wrote...

#1

11 years ago

Proteins called lamins underlie and stabilize the nuclear envelope/membrane. These proteins, when not phosphorylated, polymerize. During prophase, a cyclin-dependent kinase is activated that phosphorylates the lamins, causing them to depolymerize and the nuclear membrane to disassemble. At the end of mitosis, the lamins are dephosphorylated and re-polymerize, facilitating re-assembly of the nuclear membrane.

DAV620 Author

wrote...

#2

11 years ago

If it doesn't, then the cell can't divide. Sometimes the answer is really simple.

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