Female Sex Chromosomes, Not Just Hormones, Help Regulate Blood Pressure

According to this article: http://www.sciencedaily.com/releases/2010/03/100315161720.htm, it was determined that something in female sex chromosomes appears to trigger a rise in blood pressure after the onset of menopause. This finding challenges the current belief that sex hormones are largely responsible for regulating blood pressure. An experiment was done with mice giving female mice the XY chromosomes and the male mice XX chromosomes. In this study, mice in which the Sry gene was deleted from the Y chromosome resulted in XY females. These mice were females because they were born with ovaries.

I think that finding what else is responsible in regulating blood pressure is a benefit for sure yet, changing the sex of mice, is something that I was ethically challenged about.

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