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lovescience14 lovescience14
wrote...
10 years ago
Designate how a XXY Klinefelter man could have been produced?

A. Mother: nondisjunction of X's in anaphase I and II
    Father: normal segregation
B. Mother: normal segregation
    Father: nondisjunction of X and Y in anaphase I and II
C. Mother: normal segregation
    Father: nondisjunction of X and Y in anaphase I
D. Mother: Nondisjunction of X's in anaphase II
     Father: normal segregation
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wrote...
10 years ago
c
Post Merge: 10 years ago

also d
lovescience14 Author
wrote...
10 years ago
I agreed with C. That's what I had as well. But why do you think it could also be D?
wrote...
10 years ago
I think D could be a possibility because the 3rd and final polar body in the female waits until fertilization to complete Meiosis II, so there would still be two X chromosomes if Meiosis II didn't finish properly after fertilization. 

That being said, I would think it is much more likely that the father is to blame here, simply because mature sperm that only have a Y chromosome are much more susceptible to not survive because the X chromosome has many genes that are needed to sustain life.  This is why there is physical link between sperm during maturation, so the ones that are given the Y chromosome don't miss out on all the genetic goodness that comes from the much larger X chromosome.  Simply an educated guess here, I am not educated on the non-disjunction mechanisms of KS.

Vote: C

 
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