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Home Q & A Board Biology-Related Homework Help Anatomy and Physiology
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nadioga nadioga
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Cystic fibrosis is a genetic disease caused by mutations in the gene for a chloride ion transport protein.  The gene is on chromosome seven.  Alleles that cause the disease are recessive in comparison to the normal allele.  The phenotype includes effects on the lungs, liver, small intestine and pancreas.  Females are infertile.  In the lungs mucus accumulates, making the patients subject to chronic bacterial infections.   Cystic fibrosis is one of the most common genetic diseases in Caucasians, with a prevalence of about 1 in 400 people being carriers for a mutant allele.

Suppose a man and a woman are both carriers.  What are the possible genotypes of their gametes?  Draw a Punnett square.  What are the possible genotypes of their children?  What are the probabilities these genotypes will appear?  What are the corresponding phenotypes and their probabilities?
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how_mendelhow_mendel
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