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12 years ago
In order to pass along his genetic material, the male of the species must generate sperm. Describe the production, maturation, and release of sperm, and how the sperm reach the ova.
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12 years ago
The sperm develop from spermatogonia located within the seminiferous tubules of the testes. The spermatogonia are positioned at the outer portion of the tubule that surrounds the Sertoli cells. These cells begin to move between the Sertoli cells toward the lumen of the seminiferous tubules, going through meiosis as they traverse this gap. Development of these cells is mediated by differences between the chemical composition of the fluid within the basal and luminal compartments, which are separated by tight junctions between Sertoli cells. Differences in the composition of interstitial fluid in these compartments drives the meiosis. The Sertoli cells secrete the luminal fluid that contributes to sperm development and facilitates sperm movement into and through the tubules. In addition, Sertoli cells provide developing sperm with nutrients and release an androgen-binding protein, which acts as an androgen buffer to maintain a luminal concentration of testosterone that supports sperm development. The sperm are moved from the seminiferous tubules by the movement of fluid generated by the Sertoli cells and a peristaltic contraction of the seminiferous tubules. The sperm travel from the seminiferous tubules to the rete testes and onward to the efferent ductule until they reach the epididymis. The epididymis is a thin, coiled duct that leads to the vas deferens upon ejaculation. As the sperm pass through the epididymous, they further mature to become modal. There are three accessory glands that add fluid to the sperm. The first is the seminal vesicle, which secretes an alkaline fluid containing nutrients, enzymes, and prostaglandins into the ejaculation duct. The prostate gland releases enzymes and citrate into the urethra when the surrounding smooth muscle cells contract. Finally, the bulbourethral glands secrete a viscous, sticky mucus into the urethra to act as a lubricant.
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