Can someone please show me a simply diagram showing the effects of ras pathway. All the google diagrams suck. Half the diagrams are leaving out huge gaps like showing PI3 Kinase, but no akt!!? Some don't show myc...then some don't show what myc activates. Some show fos/jun ap1 being activated just by ras raf mek/erk which is wrong. Some are too detalied in other areas.
It's SOOO confusing because no one has bothered to put up a simple map. You have to piece a bunch of crap together. Anyone have a map that isn't SUPER detailed, but just basic and shows all the proteins? Scientists need to learn how to communicate. It seems they want to make things more difficult just to make themselves feel superior.
How do you
get to FOS/JUN? Is it differnet pathway to fos then to jun? Each step in different diagrams shows a different route when I google it.. What does FOS/JUN activate? Does it activate MDM2? Where does ETS fit in? What about ELK1
Activation of myc = ras raf merk erk? Correct? What specific genes does myc activate?
What does AKT activate/Inhibit? Bad?
He're a pathway map
http://www.sabiosciences.com/images/Ras_Pathway_680.gifIt show erk only activiating Elk1. I thought it activates FOS? What the hell?
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