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minjai0322 minjai0322
wrote...
13 years ago
1. List two of the cofactors involved in the reaction catalyzed by pyruvate dehydrogenase. What is a cofactor of an enzyme?

2. The three reactions at the junction o fTCA cycle and glycolysis are shown below:
(a)                       r1   
     Pyruvate         ?         acetyl CoA + CO2

                           r2
     malate            ?          oxaloacetate??

                                r3
  acetyl CoA + OAA   ?      citrate

at steady state are the magnitude of r1, r2 and r3 all equal?
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2 Replies

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Replies
wrote...
Valued Member
Educator
13 years ago
1.

- TPP (thiamine pyrophosphate)
- FAD+
- NAD+
- A cofactor is a non-protein chemical compound that is bound to a protein and is required for the protein's biological activity. These proteins are commonly enzymes, and cofactors can be considered "helper molecules" that assist in biochemical transformations.

2.

- pyruvate dehydrogenase complex (PDH) converts pyruvate into acetyl-CoA...
Pyruvate         ?         acetyl CoA + CO2

- malate dehydrogenase converts malate into oxalacetate and NADH

- Citrate Synthase

Slight Smile
minjai0322 Author
wrote...
13 years ago
1.

- TPP (thiamine pyrophosphate)
- FAD+
- NAD+
- A cofactor is a non-protein chemical compound that is bound to a protein and is required for the protein's biological activity. These proteins are commonly enzymes, and cofactors can be considered "helper molecules" that assist in biochemical transformations.

2.

- pyruvate dehydrogenase complex (PDH) converts pyruvate into acetyl-CoA...
Pyruvate         ?         acetyl CoA + CO2

- malate dehydrogenase converts malate into oxalacetate and NADH

- Citrate Synthase

Slight Smile

Bioman!
I always appreciate for your big help!
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