Biology Forums - Study Force

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The corona virus cases are increasing day by day.
Its a alarming situation.

The Leading Global Pharmaceutical manufacturing cos in USA, UK, Canada, France, Germany etc countries have to prepare & manufacture the Corona virus vaccine/s solution/s as quickly as possible.

Thanks & Regards,
Prashant S Akerkar

How concerned are you from a scale of 1 to 10? - 10 being terrified

Thanks.

10 - Major Alarming situation.

Its like a major fire taking place & we have to bring Fire fighters in action as quickly as possible for extinguishing the major fire.

Similarly Corona COV -19 vaccines have to be manufactured as quickly as possible by global Pharmaceutical manufacturing companies in USA, UK, Canada, France, Germany etc.

Testing will also going to be consuming time after vaccines are manufactured as the vaccines should work properly for preventing COV - 19 virus entering the Human anatomy system.

Thanks & Regards,
Prashant S Akerkar

Vaccines take a long time to make, 12 to 18 months, and they aren't risk-free. For example, a recipient can have an allergic reaction to one of its components and die because of it. I wouldn't rush into using a vaccine right away, at the end of the day you don't know how it was made, especially if it's released too quickly. It needs to be tested again and again, and a wait period to see if it causes any side-effects.

Thanks.

I agree with you. The COV -19 cure & vaccine drug manufacturing & testing will consume time.

WHO has declared COV -19 as global Pandemic.

Top 10 pharmaceutical cos.

https://www.proclinical.com/blogs/2019-3/the-top-10-pharmaceutical-companies-in-the-world-2019

Thanks & Regards,
Prashant S Akerkar

Thank you.

Can't the COVID-19 vaccine creation & testing time be reduced to 3 months?

Thanks & Regards,
Prashant S Akerkar

Thanks.

Reference : Pangolin

https://www.nytimes.com/2020/02/10/science/pangolin-coronavirus.html

Thanks & Regards,
Prashant S Akerkar

👍👍 Very informative, thanks


Certainly, but you risk not accounting for the long term impact it could have on the recipient. Many medical dictionaries will define "chronic" as an illness that persists for six months or longer and "acute" as one that persists for less than six months. 3 months doesn't give researchers enough time to properly conclude.

https://www.aljazeera.com/news/2020/01/countries-confirmed-cases-coronavirus-200125070959786.html

https://en.wikipedia.org/wiki/Antarctica

https://worldpopulationreview.com/countries/countries-in-antarctica/

Currently 177 countries in continents across the globe have been affected by the COVID -19 pandemic except Antartica continent.

COVID-19 Vaccine creation with 100% proper results for virus prevention entering the human anatomy system is the need of the hour in this crisis situation along with stopping the current virus spread in every country as well as testing & curing the affected COVID - 19 patients.

Do you agree?

Thanks & Regards,
Prashant S Akerkar

Preventing the virus from spreading by encouraging social distancing for the time being is best. Prevention through a vaccine is equally important, but that won't have one practically for another 12 months.

I agree 👍

Thank you.

https://en.wikipedia.org/wiki/Antarctica

Do you feel there could also be identified COVID-19 cases in Antarctica continent?

Or

It is unlikely there will be no COVID-19 cases in Antarctica continent?

Thanks & Regards,
Prashant S Akerkar

Barely anyone lives, stays long-term, or travels there, so I  doubt it.

Thank you.

Can the COVID-19 affected human being transmit the virus to Pets viz Dogs, Cats, Horse, Rabbit, Turtle, Tortoise, Parrot etc?

Thanks & Regards,
Prashant S Akerkar

I'd take precautions no matter what. I'm quite certain it can be transmitted, since bats are known to have it, and likely the vector source to human beings

Thank you.

Will the same testing kits for testing Human samples for COVID-19 +ve or -ve work for Cats, Dogs & other pets?

Thanks & Regards,
Prashant S Akerkar

Not necessarily. From what I understood, it's catered to humans only. The immune system of cats, and other pets can differ substantially.

Thank you.

Do you feel there could also be chances of Cats & Dogs as carrier hosts along with Pangolin , Bats & Humans for COVID - 19?

Thanks & Regards,
Prashant S Akerkar

Thank you.

Testing kits for Pets viz Cats, Dogs, Horses, Rabbits, Tortoises, Turtles, Parrots etc will be required to test whether they have been transmitted the COVID-19.

Thanks & Regards,
Prashant S Akerkar

I think recently they found that a dog died after being infected, hence they can be carriers. At the end of the day, they are mammals, and we share a lot of the same physiology as it. It all boils down to how strong their immune system is.

Thanks.

COVID-19 news.

Dated 11th Feb 2020

https://www.medicalnewstoday.com/articles/mnt-73692


Dated 26th March 2020

https://www.bbc.com/news/amp/science-environment-52048195


Thanks & Regards,
Prashant S Akerkar

https://www.medicalnewstoday.com/articles/mnt-73692


Wow, very compelling evidence

https://www.bbc.com/news/amp/science-environment-52048195


Nasty

Thanks.

Useful site for latest updates.

http://www.niaid.nih.gov/research/lab-virology-new

Thanks & Regards,
Prashant S Akerkar

Thanks.

https://www.news18.com/news/world/pet-cat-contracts-covid-19-from-infected-owner-in-belgium-health-authorities-2554317.html

Thanks & Regards,
Prashant S Akerkar

The frightening thing is the prospect that our pets can be vectors of the epidemic in our society. That would be a game-changer in all this, then I think it'd be as bad as they say it's going to be. For now, I'm still a bit skeptical.

Thank you.

There are couple of questions from my end.

1   Is Tracing the correct Host carrier for COVID-19 not a mandatory requirement or useful for designing & developing a vaccine?

2 Is Tracing the correct Host carrier for COVID-19 not a mandatory requirement or useful for developing a cure or treatment?

Potential Host carriers identified for COVID-19 are
Pangolin, Bat, Dog, Cat.

What's your opinion?

Thanks & Regards
Prashant S Akerkar

Thanks.

News updates.

https://www.livemint.com/news/world/57-year-old-wuhan-market-shrimp-seller-may-be-covid-19-patient-zero-report-11585396304490.html

Thanks & Regards,
Prashant S Akerkar

It's not mandatory, but it's important that we know the source just for reference. We do not need the source to develop a working vaccines, because we can harvest the virus from any host, such as a human.

The same also applies to question 2. The source is important to compare genomes, but apart from that it's not mandatory.

Bats, Pangolin, for sure. There's not enough data to suggest that dogs and cats act as vectors for its spread.

Thank you.

So the Best input sources of designing & developing vaccine as well as cure for
COVID-19 would be Positive tested Human Being samples affected by COVID-19?

Can we also take Cats & Dogs samples who have tested positive COVID-19 for creating vaccine & cure medicine?

Thanks & Regards,
Prashant S Akerkar

As a scientist, you'd need to harvest the virus from a host, preferably a human, but an animal could do as well. You model the vaccine based off of a protein that's prominent in the virus' outer shell. This was protein-like molecule would get injected into the recipient hoping to receive immunity so that his/her immune system learns of the foreign pathogen before an actual attack occurs.

Thanks.

A difficult question to answer for all of us.

When will the COVID-19 Pandemic in all countries be eliminated completed?

Is this only possible realistically when the COVID-19 vaccines will be designed, developed , tested to work properly after 12 -18 months ?. But this is a long period.

But unfortunately as we get the COVID-19 cases data across the globe, they are rising day by day with recorded deaths mounting.

Thanks & Regards,
Prashant S Akerkar

Eventually the spread will stop growing exponentially. It will taper off within 2 weeks, as we've seen in countries that have placed the appropriate measures, like quarantines. However, you might see another jump a few months later even after everything has subsided. This might be due to reinfection, though by then those that were infected and susceptible will already have developed immunity, so there will be less deaths. Here's a chart for the spread of ebola:

(https://www.economist.com/sites/default/files/images/2015/12/blogs/graphic-detail/20160116_woc998_0.png)

We're hoping for this outcome. Eventually we will have tested and developed medicines that can combat the virus, including vaccines if necessary.

Thank you.

COVID-19 response to temperature.

https://www.google.com/search?sxsrf=ALeKk02snPRNO8Hzas9XUz9UNj_PXDdFMQ%3A1585934233602&source=hp&ei=mW-HXtvGIt6DrtoP04-woAs&q=COVID-19+response+to+temperature&oq=COVID-19+response+to+temperature&gs_lcp=ChFtb2JpbGUtZ3dzLXdpei1ocBAMOgQIIxAnOgUIABCDAToCCAA6BAgAEAM6BQghEKABUM8SWO_BAWCzyAFoA3AAeACAAfEFiAHzMpIBDjAuMjEuNS4yLjAuMS4xmAEAoAEB&sclient=mobile-gws-wiz-hp

Do you feel the COVID-19 cases would had been less during summer season (hot) where the temperature is high rather than in winter season (cold) where the temperature is low across the countries?

For example : USA case study.

When is the summer season period - months period in USA?.

If currently is the winter season in USA i.e. April month, so the COVID-19 cases will be more. Had it been Summer season, the COVID-19 cases would had been drastically less?

Your opinion & views regarding the same.

Thanks & Regards,
Prashant S Akerkar

Thank you.

https://www.google.com/search?sxsrf=ALeKk03-3EekhDfMcFBmo7m0_RT1KcHU1g%3A1585936343743&source=hp&ei=13eHXqXAK_6D4-EP2KCrgAI&q=temperature+in+mumbai&oq=Temper&gs_lcp=ChFtb2JpbGUtZ3dzLXdpei1ocBABGAAyDAgjECcQnQIQRhCAAjIECCMQJzIECCMQJzIFCAAQkQIyAggAMgIIADICCAAyAggAOgcIIxDqAhAnOgUIABCDAToFCC4QgwE6BwgAEBQQhwJQsRhY5iZgti1oAXAAeACAAaUGiAGZEZIBCzAuMS4zLjUtMS4xmAEAoAEBsAEI&sclient=mobile-gws-wiz-hp

Today's temperature in Mumbai city, Maharashtra state, India is
29°c. This is the summer period in India and the temperature will go higher in May month.

So your views & opinion regarding COVID-19 response to seasons, climates, temperature.

Thanks & Regards,
Prashant S Akerkar

Thank you.

https://www.google.com/search?q=Current+temperature+in+New+York&oq=Current+temperature+in+New+York&aqs=chrome..69i57j0l3.17402j1j7&client=ms-android-lava&sourceid=chrome-mobile&ie=UTF-8

Today's temperature in New York is 11°c.

So the cases are high due to 11°c, apart from it, New York is a metropolitan city if i am not wrong, social distancing is a precautionary measure.

Across the 50 states & cities, the current season in April month is winter(cold) in USA?

Are there any States, cities in USA where the temperature is relatively higher in April month?

In those states, cities, can you please provide me the COVID-19 cases data?

Thanks & Regards,
Prashant S Akerkar


Are there any states,

Thanks & Regards,
Prashant S Akerkar

Thanks.

https://www.ndtv.com/health/coronavirus-can-increase-in-temperature-kill-covid-19-experts-weigh-in-2196557

https://www.google.com/search?sxsrf=ALeKk009qP1CCMY5elly2_hg_f_RxTsXJQ%3A1585972214013&source=hp&ei=9QOIXuvTO4XdrQHk572ACA&q=summer+period+in+usa&oq=Summer+peri&gs_lcp=ChFtb2JpbGUtZ3dzLXdpei1ocBABGAQyBAgjECcyBAgAEEMyAggAMgIIADICCAAyAggAMgIIADICCAA6BwgjEOoCECc6BAguEEM6BwgAEBQQhwJQhCJYhV5gjm5oAXAAeACAAc0DiAHnD5IBCTAuOC4xLjAuMZgBAKABAbABCA&sclient=mobile-gws-wiz-hp

The Summer period in USA starts from June and lasts till August month.

Had it been June,July, August month in USA, then the COVID-19 cases which we are seeing today having a spike in New York & other states would have been relatively quite lower?

Thanks & Regards,
Prashant S Akerkar

Thanks.

https://www.amazon.com/dp/B01M6BDXMD/ref=kwrp_li_stl_nodl

Nice book. Paperback edition not available.

Reference : Chapter 95 on Influenza & Coronaviruses.

I have not purchased Kindle e-reader device.

Downloaded Amazon Kindle app on my Android phone.

Thanks & Regards,
Prashant S Akerkar

Thanks.

https://www.google.com/search?client=ms-android-lava&biw=360&bih=592&sxsrf=ALeKk02vG97tH3oMhYcpLkB4ETcoRV6FdA%3A1585983202711&ei=4i6IXrnlKsbt9QOAlJSgDQ&q=COVID-19+seasonal+flu%3F&oq=COVID-19+seasonal+flu%3F&gs_lcp=ChNtb2JpbGUtZ3dzLXdpei1zZXJwEAw6BAgjECdQ_hZY_hZgox1oAHAAeACAAewBiAHAA5IBAzItMpgBAKABAQ&sclient=mobile-gws-wiz-serp#scso=_6C6IXoz8I8ml9QOexJTAAw10:400

Thanks & Regards,
Prashant S Akerkar

I'm not sure. At first I thought it would slow down the spread in the US (as what happens with the flu), but then I noticed that it has spread to warmer climates already. Maybe seasonal changes have an effect that hasn't been understood, and could halt it here in the US.

It's more prevalent in New York because the climate is more moderate, as you pointed out, and also the city is very populated. Cold temperatures and overpopulation leads to easy spread. New Yorkers are used to using packed subways, cramped elevators, and busy streets, so it's no wonder it spread like wildfire. Places like Mumbai also have that potential, but to a lesser extent because people spend their time outside. I also believe the sun's rays have an impact on the virus itself; the more it is exposed to sunlight, the weaker it becomes.

Thank you.

God bless USA in this moment of crisis.

Can you provide me the COVID-19 cases live data (Today's date) across the 50 states in USA?

We will analyse as why some states are having more COVID-19 cases and why some states the cases are relatively lesser.

Then we will check today's temperature in those states, cities.

Is the COVID-19 virus attacking more people who are living in cold (less temperature)
places rather than the people who are staying in places having higher temperature?.

We can come to some conclusion after getting the live data.

Apart from climate, other factors could be city population, social distancing measure awareness, Personal Hygiene, Medical facilities etc.

God bless you too.

Thanks & Regards,
Prashant S Akerkar

Thanks.

Analysis assist us after getting the Live data of COVID-19 cases across the 50 US states as

* Which States are having maximum & minimum cases, reasons for the same?.
Why in some States, there are maximum numbers, while some states are having minimum numbers?
* The States having maximum cases have to be given more attention in terms of medical facilities, social distancing awareness as the virus do not spread further.

Thanks & Regards,
Prashant S Akerkar

Thank you.

I am highly impressed with Down to earth personality of
Dr Anthony Fauci.

It is very unfortunate that as seen from the news, he is getting death threaths.

Is the news true?

Your views, opinion on Dr Fauci.

https://youtu.be/jHdblyM_3hs

Thanks & Regards,
Prashant S Akerkar

The most comprehensive one I found is this one:

https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6


It has been hit hard in warm and cold climates. I think the common denominator here is overpopulation, not temperature.


He's as talented as the president says he is, but what concerns me is if he's influenced by the wrong crowd. For example, he's friends with Bill Gates, and Bill Gates keeps advocating for mandatory vaccines, and creating "invisible ink" that will serve as markers to show whether or not you've been vaccinated. He keeps pushing these strange ideas that go against our freedom, and it concerns me that he may be influencing Dr. Fauci. Keep in mind that Bill Gates is a computer nerd, not a dedicated scientist or biologist.

Thank you.

Do you feel in this moment of crisis in USA, there should be nation wide lockdown or in specific states like New York or California or do you feel lockdown at this stage is not at all required both nation wide & states wise?

My personal opinion is after getting the live data of COVID-19 cases states wise, where the cases are surging / mounting at its peak everyday for example New York, then in those states, there should be lockdown declared.

Thanks & Regards,
Prashant S Akerkar

Thanks.

https://www.cnn.com/2020/04/05/health/young-people-dying-coronavirus-sanjay-gupta/index.html

Hope the numbers are very less.

Do the younger generation can get COVID-19 ?.

https://www.aljazeera.com/news/2020/01/countries-confirmed-cases-coronavirus-200125070959786.html

Out of 3,24,052 COVID-19 cases in USA,how many are in the 15-40 age group?

Thanks & Regards,
Prashant S Akerkar

Thanks.

https://www.wionews.com/photos/are-animals-next-see-how-many-have-tested-positive-for-covid-19-so-far-290812#march-16-290796

Thanks & Regards,
Prashant S Akerkar

The whole country needs to be in lockdown. What happens is people who are afraid may leave to another state that has fewer cases, while they are asymptomatic carriers. Therefore, they may end up spreading the virus to these places without even knowing.


The percentage remains low for younger people. However, everyone is evenly likely to get it, but only those greater than 50 are more likely to die of it if infected.

In terms of vaccines, it’s hard to right away give it hi the public because they’re different group of people, they have to factors, age, pre medical conditions etc. They still studying the structure of viruses and how they interact with human cells to make us sick.

Viruses usually cause disease by reproducing themselves many times in the body. Whereas natural viruses reproduce thousands of times during an infection, vaccine viruses usually reproduce fewer than 20 times. Because vaccine viruses don't reproduce very much, they don't cause disease, but vaccine viruses replicate well enough to induce "memory B cells" that protect against infection in the future.

the vaccine contains a synthetic version of mRNA. When injected into a muscle cell, the mRNA acts like a drill sergeant, ordering the cell to create a doppelgänger of one of the coronavirus’s surface proteins—known as “spikes,” which, together, decorate the surface of the virus, giving the appearance of a crown. The spike protein is only part of the virus and therefore won’t make a person sick. But it is a crucial component of how the virus infects a human cell.

Inside of a vaccine is a dead, a weak but alive, or just a little piece of some kind of disease-causing agent, such as a virus. When this weakened form of the pathogen is shot into your body, your immune system immediately recognizes that it's something harmful. This recognition forces it to build up a stronger immune system to that particular pathogen. The next time you are exposed to that pathogen in real life - exposed to the strong and real-life version of it - your immune system will be able to recognize it and fight it off far more quickly than had you not been vaccinated. In most cases you'll be able to prevent an entire disease process from occurring that may have even killed you had you not gotten vaccinated.

Even if the virus wanes in the warmer months, as does influenza, it will have circulated in the population already, and could reëmerge in the fall.

With that said, having to weaken the virus and injected to human body is very risky right now since they don’t have clear understanding of the structure of the viruses.

Thanks.

https://www.aljazeera.com/news/2020/01/countries-confirmed-cases-coronavirus-200125070959786.html

As we analyse the live data of COVID-19 cases across the globe, there are certain nations with more deaths happening still now.

What could be the reasons for the same?

* Medical facilities viz Ventilators, Treatment drugs, Hospital beds, Availability of Doctors, Nurses etc not adequate.

*Age group - 60 years + more

Any other factors?

Thanks & Regards,
Prashant S Akerkar

Preparedness is a key factor. Hospitals, health-care personnels, and caregivers were unprepared and unaware of the impact it had.

>90% of the medicines bought and sold in the United States come from China, as do masks, ventilators, and literally everything we purchase here in the states. This created a panic because we had to start depending on manufacturers here to start producing the necessary things we needed to combat the virus.

Another issue was knowing very little about the pathogen; while studies were available, the idea of it spreading wasn't as important to us until it started infecting people at home. We took it too lightly; our borders were open, our politicians foolishly advocated to keep living life normally and not to panic; we were even afraid to address the issue because of fear of racism.

These are some of the reasons why it spread faster than the flu. Once we have all the variables controlled, moving forward will be a different story.

If coronavirus really was as dangerous as they say it is, India would have dead bodies stacked higher than the Taj Majal in all major cities. Every day would be its own Holocaust of at least 6,000 deaths. Today would be Holacuast XXXII. India currently has 178 coronavirus deaths.

Thanks.

Current live data of COVID-19 cases across the globe.

https://www.nbcnews.com/health/health-news/coronavirus-map-confirmed-cases-2020-n1120686

https://www.aljazeera.com/news/2020/01/countries-confirmed-cases-coronavirus-200125070959786.html

Thanks & Regards,
Prashant S Akerkar

That's a good point. With a population of 1.5 million, you'd think that overpopulation would contribute to a lot more deaths than any other country. But I think it has to do with India's inefficient way of administering tests to the sick and/or the lack of equipment necessary to treat people long enough to find out if they're infected. Therefore, a lot of people go undetected and succumb to the virus without being recorded. I'd add thousands of death due to this discrepancy.

Population is one of the factors that why America has the highest death rate but Indian is very hot country and virus don’t survives in hot climate that temperature reaches 40 degree Celsius and above

Thanks.

https://www.google.com/search?client=ms-android-lava&sxsrf=ALeKk01jqtZh2xU1mkDza9RDI7cmpKVPcQ%3A1596987682860&ei=IhkwX4OFNKPez7sP6uKn4AE&q=ChAdOx1%2C+covid-19&oq=ChAdOx1%2C+covid-19&gs_lcp=ChNtb2JpbGUtZ3dzLXdpei1zZXJwEAMyBAgjECcyAggAMgIIADICCABQAFgAYJEaaABwAHgAgAHUA4gB1AOSAQM0LTGYAQDAAQE&sclient=mobile-gws-wiz-serp

I am optimistic about ChAdOx1 COVID-19 vaccine.

Your views regarding the same.

Thanks & Regards,
Prashant S Akerkar

I hope they do come up with a vaccine as soon as possible, no so much to stop its spread but to stop the hysteria people are experiencing from fear!

Thanks.

https://youtu.be/XDCk6TLzBYw

Thanks & Regards,
Prashant S Akerkar

Thanks.

https://www.aljazeera.com/news/2021/5/14/who-urges-countries-to-donate-shots-instead-of-vaccinating-kids

Thanks & Regards,
Prashant S Akerkar

Post Merge: 2 years ago

Thanks.

https://timesofindia.indiatimes.com/world/uk/vaccines-almost-certainly-less-effective-against-b1-617-2-transmission-uk-expert/articleshow/82657312.cms

Thanks & Regards,
Prashant S Akerkar

If these vaccines are not specific for different strains, than what's the point of taking them?

Thanks.

https://www.medicalnewstoday.com/articles/covid-19-us-intelligence-rules-out-biological-weapon-origin

Your views, opinion regarding the same.

Thanks & Regards,
Prashant S Akerkar

Content hidden

Thank you.

Why do you feel there is no punishment given to the nation "China" from where is the origin?

No punishment from Nato ?

No Justice for so many people who have died.
International court of Justice - Criminal case against China.

Was China creating a Biological weapon to destroy the world?

Is the origin  from Wuyahan market?
Or
A Biological weapon created in the lab?

No Justice till date  >:(

What are your views, opinion regarding the same?

Thanks & Regards,
Prashant S Akerkar

Many reports show a collaboration between the United States and China researching gain of function pathology. Since both China and USA are the economic super powers of the world, I don't see either country facing an sanctions for what prevailed in the past two years.

thank you

Thanks.

The religious shrines Temples,Mosques,Churches,Gurudwaras were closed during the COVID19 period for the Pilgrims & Devotees.

Prashant S Akerkar

Post Merge: 11 months ago

Thanks.

https://www.the-sun.com/news/3376329/france-warned-wuhan-lab-biological-arsenal-chinese-military/amp/

Prashant S Akerkar