Definition for Difference between revisions of "Prokaryotic initiation factor-3"
From Biology Forums Dictionary
(Created page with "Prokaryotic initiation factor-3 (IF3) is a prokaryotic initiation factor. IF3 is not universally found in all bacterial species but in E. coli it is required for the 30S subunit ...") |
|||
| Line 1: | Line 1: | ||
| − | Prokaryotic initiation factor-3 (IF3) is a prokaryotic initiation factor. IF3 is not universally found in all bacterial species but in E. coli it is required for the 30S subunit to bind to the initiation site in mRNA. In addition, it has several other jobs including the stabilization of free 30S subunits, enables 30S subunits to bind to mRNA and checks for accuracy against the first aminoacyl-tRNA. It also allows for rapid codon-anticodon pairing for the initiator tRNA to bind quickly to. IF3 is required by the small subunit to form initiation complexes, but has to be released to allow the 50S subunit to bind. | + | Prokaryotic initiation factor-3 (IF3) is a prokaryotic initiation factor. IF3 is not universally found in all bacterial species but in ''E. coli'' it is required for the 30S subunit to bind to the initiation site in mRNA. In addition, it has several other jobs including the stabilization of free 30S subunits, enables 30S subunits to bind to mRNA and checks for accuracy against the first aminoacyl-tRNA. It also allows for rapid codon-anticodon pairing for the initiator tRNA to bind quickly to. IF3 is required by the small subunit to form initiation complexes, but has to be released to allow the 50S subunit to bind. |
Latest revision as of 15:54, 25 September 2014
Prokaryotic initiation factor-3 (IF3) is a prokaryotic initiation factor. IF3 is not universally found in all bacterial species but in E. coli it is required for the 30S subunit to bind to the initiation site in mRNA. In addition, it has several other jobs including the stabilization of free 30S subunits, enables 30S subunits to bind to mRNA and checks for accuracy against the first aminoacyl-tRNA. It also allows for rapid codon-anticodon pairing for the initiator tRNA to bind quickly to. IF3 is required by the small subunit to form initiation complexes, but has to be released to allow the 50S subunit to bind.