Definition for Entner-Doudoroff pathway
From Biology Forums Dictionary
The Entner–Doudoroff pathway describes an alternate series of reactions, that catabolize glucose to pyruvate using a set of enzymes different from those used in either glycolysis or the pentose phosphate pathway.
Distinct features of the Entner–Doudoroff pathway are that it:
- Occurs only in prokaryotes.
- Uses 6-phosphogluconate dehydratase and 2-keto-3-deoxyphosphogluconate aldolase to create pyruvates from glucose.
- Has a net yield of 1 ATP for every one glucose molecule processed, as well as 1 NADH and 1 NADPH. By comparison, glycolysis has a net yield of 2 ATP and 2 NADH for every one glucose molecule processed.