Definition for Difference between revisions of "Entner-Doudoroff pathway"

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The Entner–Doudoroff pathway describes an alternate series of reactions, that catabolize glucose to pyruvate using a set of enzymes different from those used in either glycolysis or the pentose phosphate pathway.
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The '''Entner–Doudoroff pathway''' describes an alternate series of reactions, that catabolize glucose to pyruvate using a set of enzymes different from those used in either glycolysis or the pentose phosphate pathway.  
  
Distinct features of the Entner–Doudoroff pathway are that it:
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Distinct features of the Entner–Doudoroff pathway are that it:  
  
[x] Occurs only in prokaryotes.
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*Occurs only in prokaryotes.  
[x] Uses 6-phosphogluconate dehydratase and 2-keto-3-deoxyphosphogluconate aldolase to create pyruvates from glucose.
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*Uses 6-phosphogluconate dehydratase and 2-keto-3-deoxyphosphogluconate aldolase to create pyruvates from glucose.
[x] Has a net yield of 1 ATP for every one glucose molecule processed, as well as 1 NADH and 1 NADPH. By comparison, glycolysis has a net yield of 2 ATP and 2 NADH for every one glucose molecule processed.
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*Has a net yield of 1 ATP for every one glucose molecule processed, as well as 1 NADH and 1 NADPH. By comparison, glycolysis has a net yield of 2 ATP and 2 NADH for every one glucose molecule processed.

Latest revision as of 21:48, 24 February 2014

The Entner–Doudoroff pathway describes an alternate series of reactions, that catabolize glucose to pyruvate using a set of enzymes different from those used in either glycolysis or the pentose phosphate pathway.

Distinct features of the Entner–Doudoroff pathway are that it:

  • Occurs only in prokaryotes.
  • Uses 6-phosphogluconate dehydratase and 2-keto-3-deoxyphosphogluconate aldolase to create pyruvates from glucose.
  • Has a net yield of 1 ATP for every one glucose molecule processed, as well as 1 NADH and 1 NADPH. By comparison, glycolysis has a net yield of 2 ATP and 2 NADH for every one glucose molecule processed.