Definition for Difference between revisions of "Dosage compensation"
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(Created page with "The phenonomen that gene dosage is compensated between males and females. In mammals, the inactivation of one X chromosome in the female reduces the number of expressed copies (d...") |
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− | The phenonomen that gene dosage is compensated between males and females. In mammals, the inactivation of one X chromosome in the female reduces the number of expressed copies (doses) of X-linked genes from two to one. | + | 1) The phenonomen that gene dosage is compensated between males and females. In mammals, the inactivation of one X chromosome in the female reduces the number of expressed copies (doses) of X-linked genes from two to one. |
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+ | 2) Dosage compensation, also known as '''Ohno's Hypothesis''', is a hypothetical genetic regulatory mechanism which operates to equalize the phenotypic expression of characteristics determined by genes on the X chromosome so that they are equally expressed in the human XY male and the XX female. |
Latest revision as of 14:20, 28 September 2013
1) The phenonomen that gene dosage is compensated between males and females. In mammals, the inactivation of one X chromosome in the female reduces the number of expressed copies (doses) of X-linked genes from two to one.
2) Dosage compensation, also known as Ohno's Hypothesis, is a hypothetical genetic regulatory mechanism which operates to equalize the phenotypic expression of characteristics determined by genes on the X chromosome so that they are equally expressed in the human XY male and the XX female.