Definition for Difference between revisions of "Nonsense mutation"
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(Created page with "A mutation that changes a normal codon into a stop codon; this causes translation to be terminated earlier than expected, producing a truncated polypeptide.") |
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| − | A mutation that changes a normal codon into a stop codon; this causes translation to be terminated earlier than expected, producing a truncated polypeptide. | + | 1) A mutation that changes a normal codon into a stop codon; this causes translation to be terminated earlier than expected, producing a truncated polypeptide. |
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| + | 2) A nonsense mutation is also a change in one DNA base pair. Instead of substituting one [[amino acid]] for another, however, the altered DNA sequence prematurely signals the cell to stop building a protein. This type of mutation results in a shortened protein that may function improperly or not at all. | ||
Latest revision as of 22:27, 9 February 2014
1) A mutation that changes a normal codon into a stop codon; this causes translation to be terminated earlier than expected, producing a truncated polypeptide.
2) A nonsense mutation is also a change in one DNA base pair. Instead of substituting one amino acid for another, however, the altered DNA sequence prematurely signals the cell to stop building a protein. This type of mutation results in a shortened protein that may function improperly or not at all.