Definition for Dosage compensation
From Biology Forums Dictionary
1) The phenonomen that gene dosage is compensated between males and females. In mammals, the inactivation of one X chromosome in the female reduces the number of expressed copies (doses) of X-linked genes from two to one.
2) Dosage compensation, also known as Ohno's Hypothesis, is a hypothetical genetic regulatory mechanism which operates to equalize the phenotypic expression of characteristics determined by genes on the X chromosome so that they are equally expressed in the human XY male and the XX female.
