Definition for Aspartate transcarbamoylase
From Biology Forums Dictionary
The "hemoglobin of enzymology", ATCase is the most extensively-studied example of an allosteric enzyme. The enzyme from E. coli is a dodecamer consisting of six catalytic subunits and six regulatory subunits. ATCase catalyzes the first step in pyrimidine biosynthesis, namely the addition of carbamoyl phosphate to L-aspartate to form N-carbamoylaspartate and phosphate.
