Definition for Inhibitory postsynaptic potential (IPSP)
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1) The response from an inhibitory neurotransmitter hyperpolarizing the postsynaptic membrane, which reduces the likelihood of an action potential.
2) An inhibitory postsynaptic potential is a synaptic potential that decreases the chance that a future action potential will occur in a postsynaptic neuron - inhibitory presynaptic neurons release neurotransmitters which then bind to the postsynaptic receptors; this induces a postsynaptic conductance change as ion channels open or close - inhibits the next neuron and is dependent upon amount of binding of inhibitory transmitmitter substance.
