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SlideshowReport

Mammalian TLRs: specificities, basic signaling mechanisms, and cellular responses

Description
Ligands for Toll-like Receptors (TLRs) are shown together with dimers of the TLRs that specially bind them.  Note that some TLRs are expressed in endosomes and some on the cell surface.  The basic steps in TLR signaling, illustrated only for TLR2 and TLR4, are applicable to all TLRs.  
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