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SlideshowReport

The sequence and postulated structure of glycophorin A

Description
This protein was the first integral membrane protein to be sequenced. The external (N-terminal) domain carries 15 O-linked and one N-linked oligosaccharides; together these constitute ~60% of the total protein mass.

The single transmembrane helix is highly hydrophobic.
The cytosolic C-terminal domain is quite hydrophilic.
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