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SlideshowReport

Activation of chymotrypsinogen

Description
A series of cleavages produces the enzyme chymotrypsin, with the disulfide bonds continuing to hold the structure together.

The initial cleavage between amino acids 15 and 16 (arrow) results in the formation of p-chymotrypsin.

Subsequent removal of the segments shown in black yields a-chymotrypsin.
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