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SlideshowReport

Mouse Cell Nuclei During Meiosis

Description
Fluorescence micrograph of mouse cell nuclei during meiosis.

Blue stain: DNA; green: paired-up chromosomes before crossing over;
Red stain: BRCA1, which is clustered around telomeres and the sex chromosomes.

This checkpoint protein is involved in DNA repair in mitosis (DNA damage) and meiosis (sealing crossover breaks), and in X chromosome inactivation.
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