Top Posters
Since Sunday
I
3
p
2
w
2
y
2
J
2
Q
2
r
2
o
2
e
2
j
2
d
2
T
2
SlideshowReport

Structure and mechanism of CRISPR–cas in microbes

Description
Unique spacer (a) sequences W 91% Repeat sequences cas operon M CRISPR trachNA Transcription (b) AMA/W Precursor chNA l Processing via cas-encoded RNase AR /\R “M dsDNA cleavage occurs trachNA—chNA-Cas complex at site of base pairing of chNA and target DNA. Invading phage (C) New spacer or plasmid DNA / filol I I Ii’lg-B—l—l-E- Integrationk \/\ \AV\ V\ \Cas-mediated processing? Recognition of foreign DNA Invading phage or plasmid DNA (d) Target r: , A _’ Targeting of DNA Upstream Target Downstream "°"'5e'f DNA CR'SPR _’ Protection DNA Repeat Spacer Repeat of self DNA
Related Images
Add Comment
Explore
Post your homework questions and get free online help from our incredible volunteers
  268 People Browsing
Show Emoticons
:):(;):P:D:|:O:?:nerd:8o:glasses::-):-(:-*O:-D>:-D:o):idea::important::help::error::warning::favorite:
Your Opinion
How often do you eat-out per week?
Votes: 81