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itzresonance itzresonance
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6 years ago
In a lysosomal storage disease, newly synthesized lysosome hydrolases are secreted from the cells rather than being delivered to the lysosomes. What is one possible mechanism for this result?
 
  A) The cis-Golgi network lacks a proton gradient.
  B) The ER is unable to produce lysosomal vesicles.
  C) Lysosomal enzymes are not phosphorylated in the rER.
  D) Mannose is not phosphorylated in the cis-Golgi network.
  E) All the hydrolase genes are mutated, resulting in synthesis by ribosomes free in the cytoplasm rather than on the endoplasmic reticulum membrane.
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alimoreyalimorey
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