Which of the following is a medication that has been found to work in a completely new way in the ...

C

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A Incorrect. Methotrexate (Rheumatrex) is an antirheumatic and antineoplastic agent used in JRA. It is usually the first SAARD used.
B Incorrect. Hydrochloroquine (Aralen) is an anti-malarial drug used to treat JRA. It decreases inflammation by decreasing the production of prostaglandin.
C Correct. Etanercept (Enbrel) is a medication that has been found to work in a completely new way in the treatment of JRA. Etanercept works by interrupting the inflammatory process, by blocking the cytokine tumor necrosis factor.
D Incorrect. Sulfasalazine (Azulfidine) is a slow acting antirheumatic drug (SAARDs) that acts as an antibiotic and anti-inflammatory drug.