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Home Q & A Board Biology-Related Homework Help Anatomy and Physiology
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colleen colleen
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10 years ago
When the kidney goes into failure, one of the signs that doctors will see is that red blood cells will crenate (shrivel up). Why does this happen in kidney failure? What process is occurring to the blood cells?
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10 years ago
Because the kidney is failing to filter particles out of the blood effectively, the plasma becomes hypertonic or hyperosmotic in comparison to the intracellular compartment of the blood cell. Since the cell membrane is impermeable to the ions, but permeable to water, water will leave the cell to try to balance the tonicity and osmolarity with the plasma and in the process the cell will shrink.
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