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Home Q & A Board Biology-Related Homework Help Medicine Pharmacology (Moderator: DelightfulMind)
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tperry2377 tperry2377
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6 years ago
A patient with second-degree burns is treated with silver sulfadiazine (Silvadene).
 
  A nursing student asks the nurse about the differences between silver sulfadiazine and mafenide (Sulfamylon), because the two are similar products, and both contain sulfonamides. What does the nurse tell the student about silver sulfadiazine?
  a. It causes increased pain when the medication is applied.
  b. It has a broader spectrum of antimicrobial sensitivity.
  c. It has antibacterial effects related to release of free silver.
  d. It suppresses renal excretion of acid, causing acidosis.
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#1
6 years ago
ANS: C
Silver sulfadiazine has antibacterial effects primarily related to the release of free silver and not to the sulfonamide portion of the molecule. Unlike mafenide, silver sulfadiazine reduces pain when applied. Silver sulfadiazine and mafenide have similar antibacterial effects. Because silver sulfadiazine does not suppress renal excretion of acid, it has fewer systemic effects.
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