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swimgal16 swimgal16
wrote...
Posts: 549
Rep: 1 0
6 years ago
According to the Fick principle, if O2 consumption remains constant, an increase in cardiac out-put will manifest itself as which of the following?
 
  a. Decrease in the CaO2  CO2.
  b. Increase in the CaO2.
  c. Increase in the CaO2  CO2.
  d. Decrease in the CO2.



Q. 2  At body temperature, how much O2 will physically dissolve in plasma at a PO2 of 40 mm Hg?
 
  a. 0.12 ml/dl
  b. 0.20 ml/dl
  c. 0.30 ml/dl
  d. 1.34 g/dl



Q. 3  Under normal physiologic circumstances, how many milliliters of O2 are capable of combining with 1 g of Hb?
 
  a. 0.003 ml
  b. 0.450 ml
  c. 0.820 ml
  d. 1.340 ml



Q. 4  Given the following blood parameters, compute the total O2 content (dissolved + HbO2) of the blood in ml/dl: Hb = 18; PO2 = 40 mm Hg; SO2 = 73.
 
  a. 16.5 ml/dl
  b. 17.7 ml/dl
  c. 18.6 ml/dl
  d. 19.5 ml/dl



Q. 5  At a PaO2 of 65 mm Hg, what is the approximate saturation of Hb with O2?
 
  a. 73
  b. 80
  c. 90
  d. 97



Q. 6  If the total hemoglobin content (Hb + HbO2) of a sample of blood is 20 g/dl and the oxyhemo-globin (HbO2) content is 15 g/dl, what is the HbO2 saturation?
 
  a. 17
  b. 50
  c. 75
  d. 83



Q. 7  Why is it necessary to keep the patient's PaO2 greater than 60 mm Hg?
 
  a. A level of 60 mm Hg marks the beginning of the steep part of O2Hb dissociation curve.
  b. Below the 60 mm Hg level, tissue hypoxia is ensured.
  c. Oxygen deprivation will cause severe cer-ebral vasoconstriction below 60 mm Hg.
  d. The PaCO2 will start to rise precipitously if the PaO2 falls further.
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wrote...
6 years ago
(Answer to Q. 1)  ANS: A
If the cardiac output rises and O2 consumption remains constant, the C(a)O2 will fall propor-tionately.

(Answer to Q. 2)  ANS: A
By applying Henry's law, the amount of dissolved O2 in the blood (at 37 C) can be computed with the following simple formula:
Dissolved oxygen (ml/dl) = PO2  0.003

(Answer to Q. 3)  ANS: D
In whole blood, each gram of hemoglobin can carry approximately 1.34 ml of O2.

(Answer to Q. 4)  ANS: B
Known values are (1) PO2, (2) total hemoglobin content (g/dl), and (3) hemoglobin saturation. Given these values, the following equation can be applied:
CaO2 = (0.003  PO2) + (Hbtot  1.34  SO2)

(Answer to Q. 5)  ANS: C
If some abnormality reduced the PaO2 to 65 mm Hg, the SaO2 would still be approximately 90.

(Answer to Q. 6)  ANS: C
If there were a total of 20 g/dl Hb in the blood, of which 15 g was HbO2, the SaO2 would be calculated as follows:
SaO2 () = 15  20  100 = 75

(Answer to Q. 7)  ANS: A
With a PO2 lower than 60 mm Hg, the curve steepens dramatically. Here, in the normal operating range of the tissues, even a small drop in PO2 causes a large drop in SaO2, indicating a decreasing affinity for O2. This normal decrease in the affinity of hemoglobin for O2 helps release large amounts of O2 to the tissue, where the PO2 is low. This also explains why it is necessary to keep the PaO2 higher than 60 mm Hg in clinical practice.
swimgal16 Author
wrote...
6 years ago
Face with Cold Sweat  Can you answer the others that I've posted too?
wrote...
6 years ago
I'll take a quick look at them
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