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Home Q & A Board Biology-Related Homework Help Anatomy and Physiology
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ninsta2700 ninsta2700
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2 years ago
Which description is consistent with chronic myelogenous leukemia (CML)?


▸ Defects exist in the ras oncogene, TP53 tumor-suppressor gene, and INK4A, the gene encoding a cell-cycle regulatory protein.

▸ Leukocytosis and a predominance of blast cells characterize the bone marrow and peripheral blood. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes.

▸ B cells fail to mature into plasma cells that synthesize immunoglobulins.

▸ The translocation of genetic material from genes 9 and 22 creates an abnormal, fused protein identified as BCR-ABL1.
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Pathophysiology: The Biologic Basis of Disease in Adults and Children

Pathophysiology: The Biologic Basis of Disease in Adults and Children


Edition: 8th
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SupremeDJSupremeDJ
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2 years ago
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ninsta2700 Author
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2 years ago
this is exactly what I needed
GeorgeNeist
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Yesterday
Smart ... Thanks!
halyna
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2 hours ago
You make an excellent tutor!
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