Why was The Prince so significant at this time in history?

Why was The Prince so significant at this time in history?
 
  A) It removed the church teachings from the daily lives of humans.
  B) It portrayed French royalty governing an Italian city-state.
  C) it provided a commentary on the ancient Roman Republic, where he claimed that pagans were the ones that encouraged civic pride and service, whereas early Christians had turned people away from public affairs.
  D) it encouraged revolution against the Catholic Church and the embracing of pagan religious traditions.
  E) It marks a sharp turn in Western political thought; previous political theory believed government was subject to divine law and received its authority from God.