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Home Q & A Board Biology-Related Homework Help Medicine
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MALI0157619 MALI0157619
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6 years ago
Based on changes in hepatic function in older adult patients, which adjustment should the nurse expect for oral medications that undergo extensive first-pass metabolism?
 
  a. A higher dose should be used with the same time schedule.
  b. The interval between doses should be increased.
  c. No change is necessary; metabolism will not be affected.
  d. The interval between doses should be decreased.
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#1
6 years ago
ANS: B
The interval between doses of the medication should be increased in older adult patients, because drugs that undergo the first-pass effect may not be broken down as well as in someone with full liver function.
A higher dose of the medication is not indicated, because toxic effects could occur.
A change in administration may be indicated in the older adult, because metabolism is affected in the elderly.
The interval between doses should not be decreased, but increased.
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