× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
7
6
o
5
b
4
s
3
j
3
b
3
m
3
K
3
g
3
L
3
w
3
Home Q & A Board Biology-Related Homework Help Medicine Pharmacology (Moderator: DelightfulMind)
New Topic  
Chellemonia Chellemonia
wrote...
Posts: 371
Rep: 0 0
6 years ago
A patient who is HIV-positive begins therapy with the fixed-dose combination nucleoside reverse transcriptase inhibitor (NRTI) Combivir (lamivudine/zidovudine) twice daily.
 
  The patient is in the clinic for follow-up 1 week after initiation of therapy and reports having nausea. The patient's creatinine clearance is 40 mL/minute. Based on these findings, the nurse will perform which action?
  a. Instruct the patient to take the medication 60 minutes prior to meals.
  b. Notify the provider to discuss single-dose NRTI products.
  c. Request an order for once-daily dosing of this medication.
  d. Suggest that the patient increase fluid intake.
Read 19 times
1 Reply

Related Topics

Replies
wrote...
#1
6 years ago
ANS: B
Patients should have dosage adjustments of NRTIs if creatinine clearance is less than 50 mL/min. The patient will need single-dose medications so that adjustments can be made. Taking the medication prior to meals improves absorption of didanosine but does not alter the side effect of nausea for Combivir, which should subside in the next week or so. This combination product is not given once daily. Increasing fluid intake will not affect this patient's symptoms.
New Topic      
Quick Reply
Explore
Post your homework questions and get free online help from our incredible volunteers
  1003 People Browsing
Start New Topic Take the Tour CoursesNew Study Tools Topics Trending Browse by Textbook
Live Chat
Related Images
  
 613
  
 588
  
 401
Your Opinion
Previous poll results: Who will win the 2024 president election?