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Home Q & A Board Biology-Related Homework Help Medicine Nursing and Clinical
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beaches411 beaches411
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6 years ago
Alpha-fetoprotein (AFP) is found in increased concentrations in the blood of adults who have carcinoma of the
 
  A. esophagus
  B. stomach
  C. pancreas
  D. liver
  E. colon
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#1
6 years ago
D
AFP is the major fetal plasma protein produced by the fetal liver. AFP is also produced by liver cell carcinomas, and thus in adults it is a good serological marker of hepatocellular carcinoma. Germ cell tumors containing yolk sac components also secrete AFP into the blood. Other carcinomas listed in this question do not secrete AFP. Adenocarcinomas of the colon, esophagus, stomach, and pancreas produce carcinoembryonic antigen, which can also be used as a serological tumor marker.
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