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Home Q & A Board Biology-Related Homework Help Cell Biology
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Haleyevette Haleyevette
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6 years ago
The activation of the serine/threonine protein kinase Akt requires phosphoinositide 3-kinase (PI 3-kinase) to _________.
 
  (a) activate the RTK.
  (b) create phosphorylated lipids that serve as docking sites that localize Akt to the plasma membrane.
  (c) directly phosphorylate Akt.
  (d) to create DAG.
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#1
6 years ago
(b) PI3-kinase activity causes the localization of Akt to the plasma membrane, where it is phosphorylated by another protein kinase. The RTK is activated before PI3-kinase is activated choice (a). PI3-kinase phosphorylates lipids, not proteins such as Akt choice (c). DAG is created by phospholipase C and is not involved in this particular signaling pathway choice (d).
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