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bu2fusul bu2fusul
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6 years ago
Which of the following red cell inclusions is or are often found in lead poisoning?
 
  a. Howell-Jolly bodies
  b. Basophilic stippling
  c. Heinz bodies
  d. Cabot rings
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6 years ago
ANS: B
Basophilic stippling, sometimes quite coarse, is characteristic of lead poisoning. Lead interferes with the breakdown of pyrimidine 5-nucleotides, which in turn are believed to retard the breakdown of ribosomal ribonucleic acid (RNA), thus leading to stippling.
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