1) In one set of experiments she succeeded in decreasing methylation of histone tails. Which of the following results would she most likely see?
Select one:
A: decreased binding of transcription factors
B: decreased chromatin condensation
C: activation of histone tails for enzymatic function
D: increased chromatin condensation
E: inactivation of the selected genes
2) Put the following events describing the process of mRNA degradation by miRNA in sequential order.
1: miRNA binds to the mRNA
2: the mRNA is degraded or translation of the mRNA is halted
3: an enzyme, Dicer, cleaves the precursor miRNA into small fragments
4: one strand of the miRNA binds a protein complex, the other strand is degraded
5: a precursor miRNA forms a hairpin loop
3) Proto-oncogenes can be converted to oncogenes by various genetic changes. Which of these mechanisms is not likely to contribute to conversion to an oncogene?
Select one:
A: Extra copies of the gene are made, thereby enhancing expression.
B: A mutation occurs upstream of the gene that results in a more active promoter.
C: Chromosomes break and fragments are translocated from one chromosome to another.
D: Point mutations occur that result in a protein more resistant to degradation.
E: All of the above are mechanisms of oncogene conversion.
4) Which process below is not a regulation point for gene expression in prokaryotic cells?
Select one:
A: protein stability
B: translation
C: transcription
D: mRNA splicing
E: mRNA stability
5) The most important means of controlling gene expression in both prokaryotic and eukaryotic cells is at the level of _______.
Select one:
A: miRNAs
B: chromatin modification
C: transcription
D: translation
E: DNA packing
6) Below is a schematic of typical eukaryotic gene organization. The upstream region is to the left, section D represents the coding part of the gene. Identify the four labeled parts.
https://moodle.umkc.edu/pluginfile.php/3...
A: section A, green
B: section B, red
C: section C, blue
D: section D, yellow
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