Choose the incorrect statement regarding chaperone-assisted protein folding in bacteria.
A. The DnaJ/DnaK complex requires ATP to facilitate protein folding.
B. DnaJ and DnaK will both bind the unfolded protein.
C. A single DnaJ/DnaK complex is rarely sufficient for complete protein folding.
D. GrpE stimulates binding of ATP to DnaJ.
E. DnaJ prevents aggregation of unfolded polypeptides.
Which of the following describes the second step in a DNA polymerase reaction?
A. The 3'-OH attacks the phosphorus of the incoming dNTP.
B. Pol I translocates, positioning the newly added nucleotide in the postinsertion site.
C. Incoming dNTP enters the insertion site.
D. PPi is hydrolyzed by pyrophosphatase to prevent the back reaction.
E. After translocation, the insertion site is now available for entry of the next dNTP.
A mutation in the ruvB gene mostly likely will:
A. reduce resistance to UV light.
B. increase binding of RuvA to DNA.
C. increase binding of RuvB to DNA.
D. stabilize the Holliday intermediate.
E. increase recombination of DNA.
The molten globule model of protein folding suggests:
A. hydrogen bonding of secondary structures drives folding.
B. translation of the polypeptide is complete before folding begins.
C. each domain of a polypeptide folds independently.
D. intermediates of increasing free energy are created.
E. hydrophobic residues coalesce to form intermediate structures.
Which of the following helicase superfamilies are not known to contain a RecA-like domain?
A. superfamily 1
B. superfamily 3
C. superfamily 6
D. superfamilies 1 and 3
E. superfamilies 3 and 6
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