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ansouza ansouza
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Posts: 3
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11 years ago
i cant find out these last two questions pleasee help

when a long duration stimulus is applied, what two determinants of an action potential refractory period are being overcome?

suggest several ways to pharmacologivally overcome a neurons refractory period and therby increase the action potential frequency?
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Valued Member
11 years ago
Here
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lorilazz,  bio_man,  mlamlheat821,  elsaa,  lovely1,  cait618,  Swanny,  bnicbeck
Sunshine ☀ ☼
wrote...
11 years ago
wow what a great forum.
wrote...
Educator
11 years ago
wow what a great forum.

Sign up.
wrote...
11 years ago
Here

Thanks for the chart.  It really help me. 
wrote...
11 years ago
thanks for the help!
wrote...
11 years ago
Thank you!
wrote...
11 years ago
I think it has to do with becoming more hyperpolarized  to get back to its -70 mV.. In order for the na+ channels to open again it has to get back to being right around zero.
wrote...
11 years ago
really great chart
wrote...
11 years ago
Thanks
wrote...
11 years ago
The complete repolarization of the cell membrane potential is being overcome, without making the cell pass through hyperpolarization to get back to its -70mV.. It just gets below 0, in order for the Na+ channels to be able to open again.. This way you will have a high frequency of action potentials..
wrote...
11 years ago
Thanks so much for all this help.  I don't know how else I would understand any of this. Slight Smile
wrote...
11 years ago
thanks
wrote...
11 years ago
Thanks this chart was great when my physioex wouldn't work
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