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Astatine Astatine
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9 years ago
A mutant bacterium is isolated. This bacterial strain has the characteristic of very slow, "sickly" growth. You isolate mRNA from this bacteria to use in an in vitro translation system and note that even in vitro it is difficult to use this message and obtain protein. Of the following, which is a likely explanation for these results?   
A) There may be a mutation in the ShineDelgarno sequence of the DNA, resulting in a RNA that poorly binds the ribosome. 
B) There may be a mutation in the ribosomal rRNA recognizing the ShineDelgarno sequence of the message. 
C) This mutant may have altered tRNA molecules, such that the codon-anticodon interaction during translation is affected. 
D) These bacteria may not manufacture enough translation factors for effective translation.   
E) In this mutant, the ribosomal subunits may not associate well enough for effective translation.
Textbook 
Becker's World of the Cell

Becker's World of the Cell


Edition: 8th
Authors:
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virionvirion
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9 years ago
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Astatine Author
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9 years ago
Thanks for finding the answer, really appreciate it.
wrote...
9 years ago
It's a tricky question, glad I was able to deliver.
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