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Home Q & A Board Biology-Related Homework Help Cell Biology
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smkemper smkemper
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11 years ago
The strain has x amount of an enzyme, but a mutant detived from that strain has 1.53 of the enzyme. There is no change in the coding region of the gene.  But there is a subtitution of two A-T base pairs in the mutant for two G-C base pairs where polymerase attaches. What would explain how a mutation could produce this change in protein level and what change would occur in mRNA level?
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#1
11 years ago
The mutations affect the promoter region of the gene, making it more effective at using RNA polymerase (the GC to AT mutations could allow for easier access to the template strand by decreased hydrogen bonding). This results in increased transcription of the gene, leading to increased enzyme production.
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rizzlepuff8rizzlepuff8
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11 years ago
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