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A patient is diagnosed with valvular heart disease after experiencing rheumatic

colleen

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11 years ago

A patient is diagnosed with valvular heart disease after experiencing rheumatic

A patient is diagnosed with valvular heart disease after experiencing rheumatic heart fever. The nurse realizes this disorder is caused by which of the following?
1. molecular mimicry
2. release of hidden antigens into the circulation
3. biologic changes that caused self-antigens to produce autoantibodies
4. an autoimmune response by slow growing mycobacteria

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robertling

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11 years ago

1 -- The introduction of an antigen whose properties closely resemble those of host tissue, results in the production of antibodies that target not only the foreign antigen but also normal tissue. This is considered molecular mimicry. Heart damage in rheumatic fever is an example of the development of antibodies against normal tissue. The other choices are explanations for the development of autoimmune disorders, however, do not describe the physiology of heart damage after rheumatic heart fever.

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cheap.tb.soln

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11 years ago

1. Molecular mimicry: antibody cross-reactivity

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