Three weeks after being treated for strep throat, a patient comes into the clini

1 -- Acute proliferative glomerulonephritis is characterized by an abrupt onset of hematuria, proteinuria, salt and water retention, and evidence of azotemia that occurs 10 to 14 days after the initial infection. The urine often appears brown or cola-colored. Salt and water retention increase extracellular fluid volume, which leads to hypertension and edema. The edema is primarily noted in the face, particularly around the eyes or periorbital edema. Dependent edema, which affects the hands and upper extremities, may also be noted. Other manifestations may include fatigue, anorexia, nausea, and vomiting, and headache. Hunger (polyphagia) and polyuria are symptomatic of diabetes mellitus.