A patient with disseminated intravascular coagulation is not responding to infus

1,2 -- When bleeding is the major manifestation of disseminated intravascular coagulation (DIC), fresh-frozen plasma and platelet concentrates are given to restore clotting factors and platelets. Heparin may be administered. Heparin interferes with the clotting cascade and may prevent further clotting factor consumption due to uncontrolled thrombosis. It is used when bleeding is not controlled by plasma and platelets, as well as when the patient has manifestations of thrombotic problems such as acrocyanosis and possible gangrene. Long-term heparin therapy, by injection or continuous infusion with a portable pump, may be necessary for patients with chronic DIC. Normal saline would not help with the clotting. The diagnosis has already been determined and bone marrow aspiration would not be indicated, just a change in treatment.