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The vast majority of obese individuals have high leptin levels (db), while only a few rare obese ...

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The vast majority of obese individuals have high leptin levels (db), while only a few rare obese ...

The vast majority of obese individuals have high leptin levels (db), while only a few rare obese individuals (ob) do not produce leptin. Which of the following hypotheses explains why leptin can cure obese individuals who produce no leptin (ob) while having no effect on other obese individuals (db)?
A) Leptin has no role in regulating weight gain.
B) Leptin is involved in a negative feedback system that regulates the rate of fat metabolism.
C) Ob individuals have dysfunctional leptin receptors in the brain.
D) All of the above answers are consistent with the data.

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Biological Science, Canadian Edition

Edition: 2^nd

Authors: Freeman, Shar, Harrington

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