Top Posters
Since Sunday
I
3
3
p
2
w
2
y
2
J
2
Q
2
r
2
o
2
e
2
j
2
d
2
SlideshowReport

The Role of Parkin in Parkinson’s Disease

Description
Parkin is involved in the destruction of abnormal or misfolded proteins by the ubiquitin-proteasome system. If parkin is defective because of a mutation, abnormal or misfolded proteins cannot be destroyed, so they accumulate in the cell. If α-synuclein is defective because of a mutation, parkin is unable to tag it with ubiquitin, and it accumulates in the cell.
Related Images
Add Comment
Explore
Post your homework questions and get free online help from our incredible volunteers
  568 People Browsing
Show Emoticons
:):(;):P:D:|:O:?:nerd:8o:glasses::-):-(:-*O:-D>:-D:o):idea::important::help::error::warning::favorite:
Your Opinion
What's your favorite coffee beverage?
Votes: 305