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SlideshowReport

Dissection of myosin II by proteases

Description
Trypsin cleavage cuts through the myosin tail to produce light meromyosin (LMM) and heavy meromyosin (HMM).

Treatment of heavy meromyosin with the protease papain digests part of the stalk structure, allowing separation of the two S1 fragments from the S2 fragment.
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